Sutherlandia species are considered the ultimate adaptogens from Africa, which are natural substances that can help the body adapt to stressful situations and increase physical and mental performance. The plants of the Sutherlandia genus are considered particularly effective adaptogens and offer a variety of health benefits when consumed regularly.

Conditions that have been treated with these plants include fever, loss of appetite, indigestion, gastritis, esophagitis, stomach ulcers, dysentery, cancer (prevention and treatment), diabetes, colds and flu, cough, asthma, chronic bronchitis, kidney and liver diseases , rheumatism, heart failure, urinary tract infections, cystitis and stress and anxiety.

The plant has been used as a douche for uterine prolapse and after delivery, a decoction is taken on the same day to expel blood residue, treat pain after childbirth and support the healing and dissolution of the uterus.

Sutherlandia microphylla has been used to treat amenorrhea